The Program, 2000-2010

Established through a National Institutes of Health Center of Biomedical Research Excellence (COBRE) grant, the Center for Cancer Experimental Therapeutics (CCET) brings together researchers from the University of Kansas Lawrence campus, Kansas State University, Emporia State University and the University of Kansas Medical Center. The Center combines the resources and faculty of Kansas' institutions to create the infrastructure needed to pursue cancer-related research and experimentation at the interface between chemistry and biology. The CCET works to identify novel bioactive compounds that will be useful basic biomedical research tools and potential therapeutic agents. Scientists from the participating schools will fight cancer through research projects focusing on specific types of cancer and the discovery of new anti-cancer drugs and therapies. The grant places an emphasis on junior faculty to develop and hone their research programs and partners them with established, active, senior faculty who serve as mentors. At any given time, a total of 37 faculty and more than 60 researchers are supported by this grant annually.

The former principal investigator of the grant, Dr. Gunda Georg, was awarded two consecutive five-year (2000-2010), $10 million grants. Leadership of the grant was passed to Dr. Barbara Timmermann in January 2007 when Dr. Georg assumed the chair of the Department of Medicinal Chemistry at the University of Minnesota.

The grant also provides funds for First Awards (novel pilot projects) up to $100,000 total for two years, and for Project Awards up to $250,000 total for two years. Funding is dependent on the quality of the research proposals, investigator's needs, and the availability of funds. Additional funding in support of the grant's efforts is supplied by the University of Kansas and the Kansas Technology Enterprise Corporation.

Strong scientific proposals at the cutting edge of cancer research, interactions among investigators at the interface of chemistry and biology, along with a strong mentoring aspect, will help facilitate the eventual establishment of an NCI-designated Cancer Center at the University of Kansas Medical Center.