Pilot Projects

COBRE Pilot Projects Nov. 1, 2010 to Oct. 31, 2012

• Duy Hua - KSU
  "Identifying the molecular target of anti-breast cancer agents enhancing gap junctional intercellular communication"
• John Karanicolas - KU
  "Identifying inhibitors of protein-protein interactions using poccket optimization"
• Gerald Reeck - KSU
  "Armet tight-binding ligans in drug development"

COBRE Pilot Projects June 1, 2011 to May 31, 2013

• Qi Chen - KUMC
  "Targeting EMT for identification of inhibitors of cancer stem cells by high-throughput screening"
• Liang Xu - KU
  "Novel Beclin-mimetics for molecular cancer therapy via modulating autophagy"

COBRE Pilot Projects June 1, 2012 to May 31, 2015

• Tomoo Iwakuma - KUMC
  "Discovering drugs that induce degradation of oncogenic mutant p53"
• Kristi Neufeld - KU
  "Novel molecular cancer therapy targeting Musashi"

COBRE Pilot Projects June 1, 2013 to May 31, 2015

• Yong Zeng - KU
  "High-throughput glynomic profiling in ovarian cancer using integrated microfluidic lectin arrays"
• David Weis - KU
  "Proteome-scale discovery of ligands targeting ezrin, an osteosarcoma target"

COBRE Pilot Project June 1, 2014 to May 31, 2015

• Dan Dixon - KUMC
  "Discovering drugs that induce oncogenic mRNA degradation"